Acquired hypernatraemia is an independent predictor of mortality in critically ill patients

Serum lactate is an independent predictor of hospital mortality in critically ill patients in the emergency department: a retrospective study

BACKGROUND Elevated lactate has been found to be associated with a higher mortality in a diverse patient population. The aim of the study is to investigate if initial serum lactate level is independently associated with hospital mortality for critically ill patients presenting to the Emergency Department. METHODS Single-center, retrospective study at a tertiary care hospital looking at patien...

Association between admission hypomagnesemia mortality or mortality of critically ill patients in intensive care unit

Background: Up to now there is no study evaluating correlation between serum magnesium and morbidity or mortality in patients admitted in intensive care unit. The aim of this study is to determine the prevalence of hypomagnesemia in critically ill patients and to evaluate its association with organ dysfunction, hospitalization period and mortality. Methods: We conducted a retrospective trial ...

Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients

INTRODUCTION The endothelial specific angiopoietin (Ang)-Tie2 ligand-receptor system has been identified as a non-redundant mediator of endothelial activation in experimental sepsis. Binding of circulating Ang-1 to the Tie2 receptor protects the vasculature from inflammation and leakage, whereas binding of Ang-2 antagonises Tie2 signalling and disrupts endothelial barrier function. Here, we exa...

Growth Differentiation Factor-15 Is a Predictor of Mortality in Critically Ill Patients with Sepsis

Growth differentiation factor-15 (GDF-15) is a member of the transforming growth factor-β superfamily related to inflammation and macrophage activation. Serum concentrations of GDF-15 can predict poor survival in chronic diseases, but its role in sepsis is obscure. Therefore, we investigated GDF-15 as a prognostic biomarker in critically ill patients. We measured GDF-15 levels in 219 critically...

Red blood cell distribution width: an emerging predictor for mortality in critically ill patients?